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交通大學-生物科技學院

高 雅婷
專任師資
職稱 助理教授
合聘師資
合聘師資
專任師資
姓名 高 雅婷
聯絡電話 03-5712121*56988
電子郵件 yatingkao@nctu.edu.tw
辦公室 實驗一館111室
學歷 美國俄亥俄州立大學化學博士
專長領域 生物物理化學, 生物巨分子動態學, 飛秒生物光譜學, 單分子顯微鏡與光譜學
實驗室分機 ext56989
實驗室網址 光學生物物理實驗室
X. Zhu, L. Zhang, Y.-T. Kao, F. Xu, and W. Min*, A tunable fluorescent timer method for imaging spatial-temporal protein dynamics using light-driven photoconvertible protein, J. Biophotonics, 8, pp226-232, 2015
Y.-T. Kao, X. Zhu, F. Xu and W. Min, Focal switching of photochromic fluorescent proteins enables multiphoton microscopy with superior image contract, Biomed. Opt. Express, 3, pp1955-1963, 2012
Y.-T. Kao, X. Guo, Y. Yang, Z. Liu, A. Hassanali, Q.-H. Song, L. Wang and D. Zhong, Ultrafast dynamics of nonequilibrium electron transfer in photoinduced redox cycle: Solvent mediation and conformation flexibility, J. Phys. Chem. B, 116, pp9130-9140, 2012
Y.-T. Kao, X. Zhu, and W. Min., Protein flexibility mediated coupling between photoswitching kinetics and surrounding viscosity of a photochromic fluorescent protein. , Proc. Natl. Acad. Sci. U.S.A. , 109, pp3220-3225, 2012
Y.-T. Kao, Q.-H. Song, C. Saxena, L. Wang, A. and D. Zhong. , Dynamics and mechanism of DNA repair in a biomimetic system: flavin-thymine dimer adduct., J. Am. Chem. Soc. , 134, pp1501-1503, 2012
E. Gatzogiannis, Z. Chen, L. Wei, R. Wombacher, Y.-T. Kao, G. Yefremov, V. Cornish and W. Min. , Mapping protein-specific micro-environments in live cells by fluorescence lifetime imaging of hybrid genetic-chemical molecular rotor tag., Chem. Commun., 48, pp8694-8696, 2012
Z. Liu, X. Guo, C. Tan, J. Li, Y.-T. Kao, L. Wang, A. Sancar, and D. Zhong., Electron tunneling pathways and role of adenine in repair of cyclobutane pyrimidine dimer by DNA photolyase., J. Am. Chem. Soc., 134, pp8104-8114, 2012
X. Zhu, Y.-T. Kao and W. Min, Molecular-switch-mediated multiphoton fluorescence microscopy with high-order nonlinearity, . Phys. Chem. Lett., 3, pp2082-2086, 2012
Z. Liu, C. Tan, X. Guo, Y.-T. Kao, J. Li, L. Wang, A. Sancar, and D. Zhong, Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase, Proc. Natl. Acad. Sci. U.S.A., 108, pp14831-14836, 2011
E. Gatzogiannis, X. Zhu, Y.-T. Kao and W. Min, Observation of frequency-domain fluorescence anomalous phase advance due to dark state hysteresis, J. Phys. Chem. Lett. , 2, pp461-, 2011
C.-W. Chang, L. Guo, Y.-T. Kao, J. Li, C. Tan, T. Li, C. Saxena, Z. Liu, L. Wang, A. Sancar and D. Zhong., Ultrafast solvation dynamics at binding and active sites of photolyases, Proc. Natl. Acad. Sci. , 107, pp 2914-2919, 2010
J. Stevens, J. Link, Y.-T. Kao, C. Zang, L. Wang and D. Zhong, Ultrafast dynamics of resonance energy transfer in myoglobin: Probing local conformation fluctuations, J. Phys. Chem. B, 114, pp1498-1505, 2010
L. Zhang, Y. Yang, Y.-T. Kao, L. Wang and D. Zhong, Protein hydration dynamics and molecular mechanism of coupled water-protein fluctuations, J. Am. Chem. Soc., 131, pp10677-10691, 2009
N. Öztürk, Y.-T. Kao, C. Selby, I. Kavakli, C. Partch, D. Zhong and A. Sancar, Purification and characterization of a type III photolyase from Caulobacter crescentus, Biochemistry, 47, pp10255-10261, 2009
Y.-T. Kao, C. Tan, S.-H. Song, N. Öztürk, J. Li, L. Wang, A. Sancar and D. Zhong, Ultrafast dynamics and anionic active states of flavin cofactor in cryptochrome and photolyase, J. Am. Chem. Soc., 130, pp7695-7701, 2008
W. Qiu, T. Li, L. Zhang, Y. Yang, Y.-T. Kao, L. Wang and D. Zhong, Ultrafast quenching of tryptophan fluorescence in proteins: interresidue and intrahelical electron transfer., Chem. Phys., 350, pp154-164, 2008
N. Öztürk, Y.-T. Kao, C. Selby, I. Kavakli, C. Partch, D. Zhong and A. Sancar, Purification and characterization of a type III photolyase from Caulobacter crescentus, Biochemistry, 47, pp10255-10261, 2008
Y.-T. Kao, C. Saxena, T.-F. He, L. Guo, L. Wang, A. Sancar and D. Zhong, Ultrafast dynamics of flavins in five redox states, J. Am. Chem. Soc., 130, pp13132-13139, 2008
L. Zhang, L. Wang, Y.-T. Kao, W. Qiu, Y. Yang, O. Okobiah and D. Zhong, Mapping hydration dynamics around a protein surface, Proc. Natl. Acad. Sci. , 104, pp18461-18466, 2007
S.-H. Song, N. Öztürk, T. Denaro, N. Arat, Y.-T. Kao, H. Zhu, D. Zhong, S. M. Reppert and A. Sancar, Formation and function of flavin anion radical in cryptochrome 1 blue-light photoreceptor of monarch butterfly, J. Biol. Chem., 282, pp17608-17612, 2007
Y.-T. Kao, C. Saxena, L. Wang, A. Sancar and D. Zhong, Femtochemistry in enzyme catalysis: DNA photolyase, Cell Biochem. Biophys., 48, pp32-44, 2007
Li, A. Hassanali, Y.-T. Kao, D. Zhong and S. Singer., Hydration dynamics and time scales of couple water-protein fluctuations, J. Am. Chem. Soc. , 129, pp3376-3382, 2007
W. Qiu, Y.-T. Kao, L. Zhang, Y. Yang, L. Wang, W. Stites, D. Zhong and A. Zewail, Protein surface hydration mapped by site-specific mutations, Proc. Natl. Acad. Sci. U.S.A., 103, pp13979-13984, 2006
L. Zhang, Y.-T. Kao, W. Qiu, L. Wang and D. Zhong., Femtosecond studies of tryptophan fluorescence dynamics in proteins: Local solvation and electronic quenching, J. Phys. Chem., 110, pp1809-18103, 2006
C. Saxena, Y.-T. Kao, L. Wang, A. Sancar and D. Zhong, Direct observation of DNA repair by photolyase. , In Femtochemistry VII: Fundamental Ultrafast Processes in Chemistry, Physics, and Biology, A. W. Castleman, Jr., M. L. Kimble, eds. ,Elsevier: Amsterdam, pp407-, 2006
Y.-T. Kao, C. Saxena, L. Wang, A. Sancar and D. Zhong. , Direct observation of thymine dimer repair in DNA by photolyase, Proc. Natl. Acad. Sci. U.S.A., 102, pp16128-16132, 2005
W. Qiu, L. Zhang, Y.-T. Kao, W. Lu, T. Li, J. Kim, G. Sollenberger, L. Wang and D. Zhong., Ultrafast hydration dynamics in melittin folding and aggregation: Helix formation and tetramer self-assembly, J. Phys. Chem. B, 109, pp16901-16910, 2005
C.-W. Chang, Y.-T. Kao and E. W.-G. Diau. , Fluorescence lifetime and nonradiative relaxation dynamics of DCM in nonpolar solvent, Chem. Phys. Lett. , 374, pp110-118, 2003
Y.-T. Kao, W.-C. Chen, C.-H. Yu and I-C. Chen. , Production of HCO from propenal photolyzed at 193 nm: relaxation of excited states and distribution of internal states of fragment HCO, J. Chem. Phys. , 114, pp8964-8970, 2001
學校名稱 國家 系所 學位 期間
The Ohio State University The United States of America Department of Chemistry Doctor of Philosophy 2003.06 ~ 2010.06
National Tsing Hua University Taiwan Department of Chemistry Master of science 1998.09 ~ 2000.06
National Tsing Hua University Taiwan Department of Chemistry Bachelor of science 1994.09 ~ 1998.06
服務機關名稱 單位 職務 期間
Columbia University Department of Chemistry Postdoctoral Associate 2010.09 ~ 2012.07
National Chiao Tung University Department of Applied Chemistry Research Associate 2002.12 ~ 2003.05
Wu-Ling Senior High School Wu-Ling Senior High School Instructor in Chemistry 2001.08 ~ 2002.08
National Chiao Tung University Department biological Science and Technology Assistant professor 2012.08 ~ 迄今
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